Author

L. Roderick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Geiser· 1 shared A. Ginion· 1 shared A. Marino· 1 shared A. P. Davenport· 1 shared C. Baufays· 1 shared C. Beauloye· 1 shared C. J. Zuurbier· 1 shared C. K. Nagaraju· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

A. Geiser

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Precision sampling of discrete sites identified during in-vivo functional testing in the mammalian heart

D. Vermoortele, C. Olianti, M. Amoni, F. Giardini, S. De Buck, C. K. Nagaraju, R. Willems, L. Roderick, K. Sipido, L. Sacconi, P. Claus

The paper develops a 3D-printed targeted sampling method to accurately identify and study arrhythmogenic sites in the mammalian heart after myocardial infarction.

bioRxiv · Nov 29, 2023Bioengineering

Sodium-myo-inositol cotransporter-1, SMIT1, promotes cardiac hypertrophy and fibrosis induced by pressure overload in mice

A. Marino, J. Cumps, L. Guilbert, A. Geiser, C. Baufays, A. Ginion, L. Ferte, S. Battault, F. De Matos, J. Ambroise, C. J. Zuurbier, F. Lezoualc'h, C. Pestiaux, G. Pyka, G. Kerckhofs, , C. Beauloye

This study shows that SMIT1 promotes cardiac hypertrophy and fibrosis in mice under pressure overload by enhancing IP3/Ca2+-dependent signaling pathways.

bioRxiv · Oct 25, 2023Cell Biology

Intracellular calcium elevations drive the nucleation of FIP200- and ATG13-containing pre-autophagosomal structures that become omegasomes

M. Smith, P. Schoenfelder, M. Manifava, H. Polson, S. Tooze, L. Roderick, N. Ktistakis

This study shows that sustained intracellular calcium elevations drive the formation of FIP200- and ATG13-containing pre-autophagosomal structures called omegasomes, but not full autophagosomes.

bioRxiv · Nov 2, 2022 · PreprintCell Biology

Genes Encoding ACE2, TMPRSS2 and Related Proteins Mediating SARS-CoV-2 Viral Entry are Upregulated with Age in Human Cardiomyocytes

E. L. Robinson, K. Alkass, O. Bergmann, J. J. Maguire, L. Roderick, A. P. Davenport

This study finds that genes involved in SARS-CoV-2 entry are upregulated in aged human cardiomyocytes compared to younger ones, correlating with age.

bioRxiv · Jul 7, 2020Cell Biology