Author

L. Santhanam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

H. Wang· 3 shared J. Steppan· 3 shared K. Nandakumar· 3 shared A. Poe· 2 shared L. Pak· 2 shared R. Choi· 2 shared T. Brady· 2 shared B. P. Wodu· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPhysiology

H. Wang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Sex Differences and Role of Lysyl Oxidase Like 2 (LOXL2) in Angiotensin II-Induced Hypertension in Mice

L. Santhanam, H. Wang, M. M. Yus, T. Brady, R. Choi, K. Nandakumar, L. Smith, R. Jang, B. P. Wodu, J. D. Almodiel, L. Stoddart, D.-H. Kim, J. Steppan

This study investigates sex differences and the role of LOXL2 in Ang II-induced hypertension, finding that LOXL2 depletion protects males but worsens female aortic contractility.

bioRxiv · Dec 13, 2023Physiology

LOXL2 inhibition ameliorates pulmonary artery remodeling in pulmonary hypertension

J. Steppan, H. Wang, K. Nandakumar, A. Poe, L. Pak, T. Brady, M. Gadkari, D. E. Berkowitz, L. A. Shimoda, L. Santhanam

This study shows LOXL2 inhibition reduces pulmonary artery stiffness and improves survival in pulmonary hypertension models.

bioRxiv · Oct 24, 2023Physiology

An evolutionarily conserved olfactory receptor is required for sex differences in blood pressure

J. Xu, R. Choi, K. Gupta, H. R. Warren, L. Santhanam, J. L. Pluznick

This study identifies Olfr558/OR51E1 as an evolutionarily conserved receptor mediating sex differences in blood pressure through effects on renin, vascular reactivity, and arterial stiffness.

bioRxiv · Nov 16, 2022Physiology

A Novel In Situ Activity Assay for Lysyl Oxidases

H. Wang, A. Poe, L. Pak, S. Jandu, K. Nandakumar, J. Steppan, R. Loser, L. Santhanam

This paper develops an in situ activity assay for lysyl oxidases to detect total catalytic function in cells and tissues.

bioRxiv · Apr 30, 2021Biochemistry