Author

L. Scherpe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

D. Boehringer· 1 shared E. J. Aird· 1 shared J. E. Corn· 1 shared J. Rabl· 1 shared T. Knuesel· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

D. Boehringer

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1 paper

Recent·Most cited

SP110 sequestration of SP100 protects against toxic filaments during innate immune signaling

E. J. Aird, J. Rabl, T. Knuesel, L. Scherpe, D. Boehringer, J. E. Corn

The paper identifies SP110 as a negative regulator of type 1 interferon-driven cell death by counteracting SP100's toxic filament formation through CARD domain interactions.

bioRxiv · Apr 3, 2024Immunology