Paradox Found: Global Accounting of Lymphocyte Protein Synthesis
M. Seedhom, D. Dersh, J. Holly, M. Pavon-Eternod, J. Wei, L. Shores, A. David, J. Santos, H. Hickman, J. Yewdell
The paper measures protein synthesis rates in lymphocytes and finds that their in vivo elongation rates increase with activation, despite a high protein-to-ribosome ratio suggesting insufficient capacity for rapid division.
bioRxiv · Oct 31, 2022 · PreprintImmunology