Author

D. Dersh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Holly· 2 shared J. W. Yewdell· 2 shared A. David· 1 shared B. Wang· 1 shared C. J. Thomas· 1 shared D. W. Huang· 1 shared G. W. Wright· 1 shared H. Hickman· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

J. Holly

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Paradox Found: Global Accounting of Lymphocyte Protein Synthesis

M. Seedhom, D. Dersh, J. Holly, M. Pavon-Eternod, J. Wei, L. Shores, A. David, J. Santos, H. Hickman, J. Yewdell

The paper measures protein synthesis rates in lymphocytes and finds that their in vivo elongation rates increase with activation, despite a high protein-to-ribosome ratio suggesting insufficient capacity for rapid division.

bioRxiv · Oct 31, 2022 · PreprintImmunology

Decoding mRNA translatability and stability from 5'UTR

L. Jia, Y. Mao, Q. Ji, D. Dersh, J. W. Yewdell, S.-B. Qian

The paper uses synthetic mRNA libraries to study 5'UTR sequence elements affecting mRNA translatability and stability in mammalian cells, identifying regulatory features and decay pathways.

bioRxiv · Mar 13, 2020Biochemistry

Genome-wide Screens Identify Lineage- and Tumor Specific-Genes Modulating MHC-I and MHC-II Immunosurveillance in Human Lymphomas

D. Dersh, J. D. Phelan, M. E. Gumina, B. Wang, J. H. Arbuckle, J. Holly, R. J. Kishton, T. E. Markowitz, M. O. Seedhom, N. Fridlyand, G. W. Wright, D. W. Huang, M. Ceribelli, C. J. Thomas, J. B. Lack, , J. W. Yewdell

The paper identifies genes modulating MHC-I and MHC-II expression in lymphomas, revealing potential targets for immunosurveillance manipulation.

bioRxiv · Mar 13, 2020Cancer Biology