14K Prolactin Derived 14-Mer Antiangiogenic Peptide Targets Bradykinin-/Nitric Oxide-cGMP-Dependent Angiogenesis
J. Lee, P. Kumar, S. Natarajan, S. H. Park, S. Majumder, L. Sundaresan, K. Muralidhar, J.-S. Choi, H. J. Lee, S. Chatterjee
This study identifies a novel 14-mer antiangiogenic peptide derived from prolactin that inhibits bradykinin- and eNOS-dependent angiogenesis, showing synergistic effects with Avastin in a colon cancer model.
bioRxiv · Aug 21, 2023Cancer Biology