Author

L. T. F. Lai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Organism:human· 1 Organism:zebrafish· 1

Frequent Co-Authors

D. Matthies· 2 shared C. Nguyen· 1 shared F. Zhou· 1 shared H.-T. Lei· 1 shared J. Balaraman· 1 shared M. J. Gallenito· 1 shared T. Gonen· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBiophysics

D. Matthies

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2 papers

Recent·Most cited

Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms

L. T. F. Lai, J. Balaraman, F. Zhou, D. Matthies

This study determines the cryo-EM structures of human MRS2 with and without Mg2+ and identifies key residues and binding sites involved in Mg2+ regulation.

bioRxiv · Aug 22, 2023Biophysics

Lipid flipping in the omega-3 fatty-acid transporter

T. Gonen, D. Matthies, C. Nguyen, H.-T. Lei, L. T. F. Lai, M. J. Gallenito

This study reports cryo-EM structures of Mfsd2a, revealing the Na+-dependent lipid flipping mechanism for omega-3 fatty acid transport across the BBB and identifying disease-associated mutants.

bioRxiv · May 31, 2022Biophysics