Author

L. T. MacNeil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:C. elegans· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

L. L. Burrows· 2 shared S. L. N. Kilmury· 2 shared K. J. Graham· 1 shared R. P. Lamers· 1 shared V. A. Marko· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersMicrobiology

L. L. Burrows

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2 papers

Recent·Most cited

Hyperpiliation reduces Pseudomonas aeruginosa pathogenicity by impeding type III secretion

S. L. N. Kilmury, K. J. Graham, R. P. Lamers, L. T. MacNeil, L. L. Burrows

The paper shows that increased type IVa pili (T4aP) on Pseudomonas aeruginosa reduces virulence by interfering with the type III secretion system, independent of twitching motility.

bioRxiv · Jan 28, 2021 · PreprintMicrobiology

Pseudomonas aeruginosa type IV minor pilins and PilY1 regulate virulence by modulating FimS-AlgR activity

V. A. Marko, S. L. N. Kilmury, L. T. MacNeil, L. L. Burrows

This study shows that minor pilins and PilY1 in Pseudomonas aeruginosa regulate virulence by modulating FimS-AlgR activity, with loss of these proteins increasing AlgR activation and reducing acute virulence factors.

bioRxiv · Apr 1, 2018Microbiology