Author

L. Zandarashvili

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

B. E. Black· 2 shared B. A. Garcia· 1 shared D. Bensaddek· 1 shared K. R. Karch· 1 shared L. Jaremko· 1 shared M. Coradin· 1 shared M. Gerace· 1 shared P. Mandal· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

B. E. Black

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2 papers

Recent·Most cited

Molecular basis of UHRF1 allosteric activation for synergistic histone modification binding by PI5P

P. Mandal, Z. Yerkesh, V. Kharchenko, L. Zandarashvili, D. Bensaddek, L. Jaremko, B. E. Black, W. Fischle

This study identifies how PI5P allosterically activates UHRF1 to synergistically bind H3unmodified and H3K9me3 histone marks through conformational changes.

bioRxiv · Aug 4, 2021 · PreprintBiochemistry

Hydrogen-deuterium exchange coupled to top- and middle-down mass spectrometry enables high-resolution measurements of histone tail dynamics before and after nucleosome assembly

K. R. Karch, M. Coradin, L. Zandarashvili, Z.-Y. Kan, M. Gerace, S. W. Englander, B. E. Black, B. A. Garcia

This paper uses HDX-MS/MS with ETD to study histone tail dynamics before and after nucleosome assembly, achieving high-resolution deuterium localization.

bioRxiv · Apr 28, 2018Biochemistry