Splicing of a core clock gene regulates seasonal adaptations by a winter gating mechanism
Sergio Hidalgo, R. Del Rio, Christine A. Tabuloc, L.A. Perez Hernandez, A.L. Berry, Yao D. Cai, Kyle M. Lewald, Joanna C. Chiu
This study shows that alternative splicing of the timeless gene regulates seasonal adaptations in Drosophila by modulating PDF signaling through a winter gating mechanism.
bioRxiv · Nov 6, 2025 · PreprintNeuroscience