Genome-wide DNA bridging by H-NS reshapes the stationary phase nucleoid and transcriptional landscape
Lindsey E. Way, Xiaofeng Dai, Emma E. Wiesler, Lauren A. McCarthy, Zhongqing Ren, Gail G. Hardy, David E.H. Fuller, Labeeb Hossain, Anne S. Meyer, Elio A. Abbondanzieri, Julie S. Biteen, Xindan Wang
This study shows H-NS bridges DNA in the stationary-phase nucleoid of E. coli, leading to transcriptional repression and a shifted gene expression landscape.
bioRxiv · Oct 14, 2025 · PreprintMolecular Biology