Lindsey E. Way

This study uses live-cell single-molecule tracking to analyze how NAPs like Dps and H-NS affect HU-DNA interactions across different growth phases in E. coli.

This study identifies the role of conserved lysine residues in ParB's C-terminal domain in DNA sliding and in vivo function.

This study measures the biophysical properties of the bacterial nucleoid and shows they are dynamic, heterogeneous, and responsive to cellular processes.

This study shows Dps compacts the E. coli nucleoid and increases short-range DNA interactions without significantly affecting chromosome accessibility, dynamics, or organisation.

This study shows H-NS bridges DNA in the stationary-phase nucleoid of E. coli, leading to transcriptional repression and a shifted gene expression landscape.

This study investigates how the sliding clamp interacts with two replicative polymerases in B. subtilis, showing that PolC-DnaN binding is essential for replication while DnaE-DnaN interaction is dispensable but affects mutagenesis.