Xindan Wang

This study identifies minJ and divIVA as essential for chromosome segregation in Bacillus subtilis when SMC function is impaired, highlighting the interdependence between chromosome segregation and cell division.

This study identifies how CAP and LuxR co-regulate gene expression in Vibrio campbellii through synergistic or antagonistic promoter occupancy, revealing indirect regulation of bioluminescence.

This study identifies the regulatory mechanisms of nitrogenase in Vibrio natriegens, showing that NtrBC is not essential but important for timely expression, while NifA autoactivation suffices for nitrogenase gene expression.

This study uses live-cell single-molecule tracking to analyze how NAPs like Dps and H-NS affect HU-DNA interactions across different growth phases in E. coli.

This study identifies RicO as a protein that anchors replication origins to the membrane in S. aureus, ensuring proper chromosome segregation.

This study identifies the role of conserved lysine residues in ParB's C-terminal domain in DNA sliding and in vivo function.

This study measures the biophysical properties of the bacterial nucleoid and shows they are dynamic, heterogeneous, and responsive to cellular processes.

This study shows Dps compacts the E. coli nucleoid and increases short-range DNA interactions without significantly affecting chromosome accessibility, dynamics, or organisation.

This study shows H-NS bridges DNA in the stationary-phase nucleoid of E. coli, leading to transcriptional repression and a shifted gene expression landscape.

This study investigates chromosome segregation dynamics in Staphylococcus aureus using FROS, revealing uncoupling between cell cycle and replication, and identifying key roles for SMC-ScpAB and other proteins in chromosome organization.

The paper identifies two natural isolates of Agrobacterium tumefaciens with fused chromosomes, revealing constraints for replicon fusion and survival.

This study investigates how the sliding clamp interacts with two replicative polymerases in B. subtilis, showing that PolC-DnaN binding is essential for replication while DnaE-DnaN interaction is dispensable but affects mutagenesis.

This study shows that replisomes block SMC-mediated DNA-loop extrusion in Bacillus subtilis by restricting SMC translocation, with occasional bypass events observed.

The paper identifies two binding sites of the SinR*SlrR heteromer in the fla/che operon that cause premature termination, reducing SigD expression and motility in Bacillus subtilis.

This study characterizes the organization of Borrelia burgdorferi's segmented genome and interactions between replicons using Hi-C, revealing chromosome structure and plasmid interactions.