Proteome-scale induced proximity screens reveal highly potent protein degraders and stabilizers
Juline Poirson, Akashdeep Dhillon, Hanna Cho, Mandy Hiu Yi Lam, Nader Alerasool, Jessica Lacoste, Lamisa Mizan, Mikko Taipale
The paper identifies potent protein degraders and stabilizers using proteome-scale induced proximity screens and shows they outperform existing E3 ligases.
bioRxiv · Aug 15, 2022 · PreprintMolecular Biology