Developmental heterogeneity of microglia and brain myeloid cells revealed by deep single-cell RNA sequencing
Qingyun Li, Zuolin Cheng, Lu Zhou, Spyros Darmanis, Norma F Neff, Jennifer Okamoto, Gunsagar Singh Gulati, Mariko L. Bennett, Lu O. Sun, Laura E. Clarke, Julia Marschallinger, Guoqiang Yu, Stephen R. Quake, Tony Wyss‐Coray, Ben A. Barres
This study uses scRNA-seq to analyze microglia and myeloid cells across brain regions and developmental stages, revealing heterogeneity in postnatal microglia and their roles in disease.
Neuron · Dec 31, 2018Peer-reviewedNeuroscience