Organizing the coactivity structure of the hippocampus from robust to flexible memory
Giuseppe P. Gava, Laura Lefèvre, Tabitha Broadbelt, Stephen B. McHugh, Vítor Lopes‐dos‐Santos, Demi Brizee, Katja Hartwich, Hanna T. Sjoberg, Pavel V. Perestenko, Robert Toth, Andrew Sharott, David Dupret
The paper shows that forming a robust memory restricts hippocampal coactivity, impairing flexible memory formation, and that optogenetic suppression during robust memory formation restores flexibility.
Science · Sep 5, 2024Peer-reviewedNeuroscience