Stephen B. McHugh

This study shows that dentate spikes (DSs) during sleep reactivate memory-related neuronal patterns, supporting flexible memory, and are distinct from sharp-wave ripples (SWRs) in their structure and function.

The paper shows that forming a robust memory restricts hippocampal coactivity, impairing flexible memory formation, and that optogenetic suppression during robust memory formation restores flexibility.

This study shows that reducing serotonin transporter activity in mice enhances aversive learning and amygdala responsivity, supporting a network plasticity theory of serotonin function.