Altered postnatal chromatin development in the nucleus accumbens primes lifelong stress sensitivity
Rebekah L. Rashford, Lisa Z. Fang, Michael DeBerardine, Hye Ji J. Kim, Laura W. Hirschfield, Ella Cervi, Mason R. Barrett, Jeremy M. Thompson, Meaghan C. Creed, Catherine J. Peña
This study shows that increased H3K4me1 in the nucleus accumbens during early life primes lifelong stress sensitivity by altering chromatin structure and neuronal function.
Journal of Neuroscience · Jul 23, 2026Peer-reviewedNeuroscience