Jeremy M. Thompson

Early-life stress alters chromatin modifications in VTA to prime stress sensitivity

This study shows early-life stress alters chromatin modifications in the VTA, increasing stress sensitivity through changes in histone dynamics and Setd7 activity.

Altered postnatal chromatin development in the nucleus accumbens primes lifelong stress sensitivity

This study shows that increased H3K4me1 in the nucleus accumbens during early life primes lifelong stress sensitivity by altering chromatin structure and neuronal function.

Reduced SK channel control of mesolimbic dopamine neuron firing drives reward seeking adaptations in chronic pain

The paper identifies impaired SK channel function in mesolimbic dopamine neurons as a mechanism driving reward seeking adaptations in chronic neuropathic pain.

A simple action reduces high fat diet intake and obesity in mice

This study shows that requiring mice to perform a simple action to access high-fat diet reduces intake and prevents obesity, suggesting that easy access promotes overeating.