Author

Lauren A. Riley

Oak Ridge National Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Organism:E. coli· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adam M. GussiD· 2 shared Gara N. DexteriD· 1 shared Henri BaldinoiD· 1 shared Irenee C. PayneiD· 1 shared Jay D. HuenemanniD· 1 shared Joshua R. ElmoreiD· 1 shared Melissa P. Tumen-VelasqueziD· 1 shared Robert G. EgbertiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersGenetics

Adam M. GussORCID

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2 papers

Recent·Most cited

Simple and rapid site-specific integration of multiple heterologous DNAs into the Escherichia coli chromosome

Lauren A. Riley, Irenee C. Payne, Melissa P. Tumen-Velasquez, Adam M. Guss

The paper develops a system for rapid, site-specific integration of multiple DNA constructs into the E. coli chromosome using recombinases, demonstrating its utility by inserting DNA methyltransferases to enable transformation of Clostridium clariflavum.

Journal of Bacteriology · Jan 19, 2023Peer-reviewedGenetics

The SAGE genetic toolkit enables highly efficient, iterative site-specific genome engineering in bacteria

Joshua R. Elmore, Gara N. Dexter, Ryan M. Francis, Lauren A. Riley, Jay D. Huenemann, Henri Baldino, Adam M. Guss, Robert G. Egbert

The paper introduces SAGE, a genome engineering system for bacteria that enables efficient, iterative integration of DNA constructs without requiring selection.

bioRxiv · Jun 28, 2020 · PreprintSynthetic Biology