ImmunologybioRxivPreprint
Omega-3 Fatty Acid Synergy with Glucocorticoid in Lupus Macrophages: Targeting Pathogenic Pathways to Reduce Steroid Dependence
Lauren K. Heine, Rance Nault, Jalen Jackson…·Olivia F. McDonald
This study shows that omega-3 fatty acids and glucocorticoids synergistically suppress inflammatory gene expression in SLE macrophages, promoting a pro-resolving M2 phenotype and potentially reducing steroid dependence.
DOI 10.1101/2025.06.12.658906