Submicron-Sampling of Living Cells by Macrophages
Amy C. Fan, Rukman R. Thota, Nina Kathrin Serwas, Vivasvan S. Vykunta, Kyle Marchuk, Megan K. Ruhland, Lauren Liu, Grace Johnson, Austin W. Edwards, Matthew F. Krummel
This study reveals that macrophages sample living cells through trogocytosis-like mechanisms, leading to distinct antigen processing and differential CD4/CD8 T cell priming.
bioRxiv · Apr 10, 2025 · PreprintImmunology