Author

Lauren Monroe

Colorado State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Soham GhoshiD· 2 shared Benjamin Gadomski· 1 shared Kanita Hrustanovic· 1 shared Katie Sikes· 1 shared Kenna Thomas· 1 shared Ryan Foslien· 1 shared Samantha KaonisiD· 1 shared Scott Burlingham· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersPhysiology

Soham GhoshORCID

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2 papers

Recent·Most cited

Epigenetic Rescue of Disuse Muscle Atrophy by Histone Deacetylase Inhibitor Trichostatin A

Kanita Hrustanovic, Scott Burlingham, Katie Sikes, Ryan Foslien, Kenna Thomas, Lauren Monroe, Benjamin Gadomski, Soham Ghosh

This study shows that Trichostatin A, an HDAC inhibitor, reduces muscle atrophy and preserves nuclear organization in mice subjected to mechanical unloading.

bioRxiv · Nov 6, 2026 · PreprintPhysiology

Mechanoepigenetic Targeting of Histone Methyltransferase EZH2 Increases Potential of Scalable Manufacturing in Human Derived Primary Mesenchymal Stromal Cells

Lauren Monroe, Samantha Kaonis, Soham Ghosh

This paper identifies a mechano-epigenetic pathway involving EZH2 that drives phenotypic drift in human MSCs during expansion and shows that EZH2 inhibition preserves stemness and therapeutic potency.

bioRxiv · Dec 12, 2025 · PreprintBioengineering