Author

Samantha Kaonis

Colorado State UniversityORCID 0000-0001-5328-6004Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Lauren Monroe· 1 shared Soham GhoshiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperBioengineering

Lauren Monroe

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1 paper

Recent·Most cited

BioengineeringbioRxivPreprintDec 12, 2025

Mechanoepigenetic Targeting of Histone Methyltransferase EZH2 Increases Potential of Scalable Manufacturing in Human Derived Primary Mesenchymal Stromal Cells

Lauren Monroe, Samantha Kaonis, Soham Ghosh

This paper identifies a mechano-epigenetic pathway involving EZH2 that drives phenotypic drift in human MSCs during expansion and shows that EZH2 inhibition preserves stemness and therapeutic potency.

DOI 10.64898/2025.12.10.693526

humanATAC-seq

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