SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress
Abdallah Zayed, Camille Baranowski, Anne‐Claire Compagnion, Cécile Vernochet, Samah Karaki, Romain Durand-de Cuttoli, Estefani Saint‐Jour, Soumee Bhattacharya, Fabio Marti, Peter Vanhoutte, Moshé Yaniv, Philippe Fauré, Jacques Barik, Laurence S. Amar, François Tronche, Sébastien Parnaudeau
This study shows that SWI/SNF chromatin remodelers are essential for behavioral and transcriptional adaptations to stress and cocaine, with gene inactivation leading to resilience and reduced gene expression.
Nature Communications · Apr 4, 2022Peer-reviewedNeuroscience