Peter Vanhoutte

The paper identifies age-related changes in the hippocampus-accumbens pathway in mice and links them to cognitive decline, showing that reducing pathway excitability can improve memory.

This study shows that dopamine signaling in the medial prefrontal cortex encodes action value during reversal learning through D1/NMDA and D2/NMDA receptor heteromers.

This study shows that SWI/SNF chromatin remodelers are essential for behavioral and transcriptional adaptations to stress and cocaine, with gene inactivation leading to resilience and reduced gene expression.

This study investigates the cell-type- and region-specific role of miR-1 in modulating cocaine-seeking behaviors in mice, showing distinct effects in D1- and D2-SPNs of the dorsal striatum.

The paper shows disrupting D2-NMDA receptor heteromerization blocks cocaine's rewarding effects without affecting natural reward processing in mice and humans.

This study shows that Pyk2 in D1 receptor-expressing neurons of the nucleus accumbens modulates acute cocaine-induced locomotor responses but not sensitization or place preference.