Romain Durand-de Cuttoli

This study identifies NAc cholinergic interneurons as regulators of natural reward approach initiation by linking sensory input to motivated action.

The paper identifies synaptic bioenergetic remodeling in the mPFC after heroin abstinence, but not cocaine, and links it to relapse vulnerability.

The paper identifies a shared transcriptional network in the nucleus accumbens that supports stress resilience in both sexes and shows causal effects of hub genes.

The paper identifies sex-specific mesoscale co-activation modules in aggression-related brain networks using c-Fos imaging and network analysis in mice.

This study shows LINC00473 in mPFC modulates sex-dependent change-of-mind behavior in mice by affecting value caching and mistake weighting in a neuroeconomic task.

The paper identifies ZBTB7A as a key regulator of MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in the orbitofrontal cortex.

This study examines how diabetes affects decision-making behaviors in mice using a neuroeconomic foraging paradigm, revealing altered valuation strategies and cognitive heuristics.

The paper identifies dopaminylated proteins in the brain, including γCaMKII, and shows its role in synaptic-to-nuclear signaling and memory formation.

This study identifies H3K27me1 as a chromatin scar that mediates lifelong stress susceptibility through its role in altering gene expression in the nucleus accumbens.

This study shows that ketamine reduces stress-induced hypersensitivity to sunk costs in mice, suggesting it may improve decision-making by reducing reliance on past losses.

The paper identifies sex-specific regulation of stress susceptibility by the astrocytic gene Htra1 in mice and humans, showing differential effects on neuronal signaling and ECM integrity.

The paper identifies distinct transcriptional profiles in striatal ensembles activated during initial vs. repeated cocaine exposure, revealing differences in neuronal recruitment and memory retrieval mechanisms.

This study identifies RXR as a key regulator of drug reward sensitivity in the nucleus accumbens through transcriptional control of neuronal excitability in mice.

The paper investigates how CREB function in specific brain regions influences distinct forms of regret related to resilience and susceptibility to chronic stress in mice.

This study shows that SWI/SNF chromatin remodelers are essential for behavioral and transcriptional adaptations to stress and cocaine, with gene inactivation leading to resilience and reduced gene expression.

The paper investigates sex differences in reactive and appetitive aggression in mice using behavioral tests, revealing distinct patterns between males and females.

This study shows chronic nicotine exposure shifts decision-making strategies toward increased exploitation in a foraging task, with optogenetic manipulation of dopamine neurons replicating this effect.

This study identifies distinct dopamine circuits in the ventral tegmental area that mediate nicotine's reinforcing and anxiogenic effects through opposing responses in neurons projecting to the nucleus accumbens and amygdala.

This study shows mice generate choice variability in a deterministic task through memory-free, pseudo-random selection rather than learning complex sequences.

This study shows that somatic nicotinic acetylcholine receptors in VTA dopamine neurons modulate firing properties and reward-related behaviors through optical manipulation.