Author

Laurens Rutgers

Amsterdam UMC Location University of Amsterdam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anne M. Kokke· 1 shared Carlijn Kuijk· 1 shared Carlijn VoermansiD· 1 shared Emile van den AkkeriD· 1 shared Gerard J. van Mierlo· 1 shared Han J. M. P. VerhageniD· 1 shared Santhe A. van der Meulen· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Anne M. Kokke

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1 paper

Recent·Most cited

Optimized guide RNA selection recommendations for using spCas9 gene editing in human hematopoietic stem and progenitor cells

Han J. M. P. Verhagen, Carlijn Kuijk, Anne M. Kokke, Laurens Rutgers, Santhe A. van der Meulen, Gerard J. van Mierlo, Carlijn Voermans, Emile van den Akker

The paper evaluates sgRNA design for spCas9-RNP gene editing in HSPCs, showing in vitro screening outperforms in silico models and no adverse effects on cell function.

bioRxiv · Dec 18, 2020 · PreprintMolecular Biology