Impaired Fermentation in the Absence of Gut Microbiota Promotes Inulin-Induced Intestinal Inflammation
Edward Moncada, Paola Andino, Vignesh Nathan, Yunus E. Tuncil, Stephen R. Lindemann, Beng San Yeoh, Andrew T. Gewirtz, Tzu-Wen L. Cross, Matam Vijay-Kumar, Lavanya Reddivari
The paper shows that impaired gut microbiota fermentation of inulin leads to intestinal inflammation in mice, highlighting the importance of microbial metabolism in fiber tolerance.
bioRxiv · Nov 9, 2026 · PreprintImmunology