Author

Xingjian Bai

Purdue University;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Bruce T. LahniD· 2 shared Jack F. Hong· 2 shared Silk J. Shi· 2 shared Abigail D. CoxiD· 1 shared Amy Y. CheniD· 1 shared Amy Y. CheniD· 1 shared Arun K. BhuniaiD· 1 shared Constance A. Rich· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Bruce T. LahnORCID

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Author profile →

3 papers

Recent·Most cited

LAP-TLR2 Axis Drives Inflammatory Pathology during Listeria monocytogenes Gastroenteritis

Dongqi Liu, Shivendra Tenguria, Nicole Irizarry-Tardi, Joonyeop Franklin, Sungtae Park, Nicholas Gallina, Luping Xu, Vignesh Nathan, Xilin Li, Yang Fu, Rishi Drolia, Xingjian Bai, Zhian Gao, Lavanya Reddivari, Kurt Ristroph, , Arun K. Bhunia

This study identifies LAP-TLR2 signaling as a key driver of inflammatory pathology in Listeria monocytogenes gastroenteritis, showing its role in epithelial damage and neutrophil recruitment.

bioRxiv · Nov 6, 2026 · PreprintMicrobiology

MuteFree: A novel AAV vector system featuring mutation-free ITRs

Silk J. Shi, Yingjun Lin, Epic Z. Fu, Hermia M. Xu, Robert J. Yang, Yaphia Y. Zhao, Jason Z. Ye, Jack F. Hong, Amy Y. Chen, Xingjian Bai, Bruce T. Lahn

MuteFree eliminates ITR mutations in AAV transfer plasmids, achieving 0% mutation rates and resolving production issues in GMP manufacturing.

bioRxiv · Apr 9, 2026 · PreprintMolecular Biology

Prevalence of errors in lab-made plasmids across the globe

Xingjian Bai, Jack F. Hong, Shan Yu, David Y. Hu, Amy Y. Chen, Constance A. Rich, Silk J. Shi, Sandy Y. Xu, Daniel M. Croucher, Kristofer Joseph Mussar, Daniel W. Meng, Jane L. Chen, Bruce T. Lahn

The paper surveys lab-made plasmids globally and finds nearly half contain errors, with 40% of transfer plasmids having mutations in ITR regions due to instability.

bioRxiv · Jun 17, 2024 · PreprintMolecular Biology