Title: The RNA-binding protein TRIM71 is essential for hearing in humans and mice and regulates the timing of auditory sensory organ development
Xiaojun Li, Lin Li, Charles Morgan, Phan Q. Duy, Lale Evsen, Le T. Hao, Roxane Machavoine, Kahina Belhous, Sylvain Ernest, Françoise Denoyelle, Cyril Mignot, Frédéric Brioude, Marine Parodi, He Huang, Prathamesh T. Nadar‐Ponniah, , Angelika Doetzlhofer
This study identifies TRIM71 as essential for hearing in humans and mice, showing it regulates the timing of auditory sensory organ development and prevents premature hair cell differentiation.
bioRxiv · May 29, 2025 · PreprintNeuroscience