Author

Charles Morgan

Johns Hopkins UniversityORCID 0000-0002-8766-0954Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Charles Morgan1 paper · University of Bonn

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Angelika DoetzlhoferiD· 4 shared Prathamesh T. Nadar‐PonniahiD· 2 shared Waldemar KolanusiD· 2 shared Cyril MignotiD· 1 shared Elena Chrysostomou· 1 shared Françoise DenoyelleiD· 1 shared Frédéric BrioudeiD· 1 shared He HuangiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersDevelopmental Biology

Angelika DoetzlhoferORCID

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4 papers

Recent·Most cited

Developmental BiologybioRxivPreprintAug 20, 2026

Loss of Zbtb20 disrupts cochlear supporting cell differentiation and maturation and extends the postnatal hair cell regenerative window in mice.

Charles Morgan, Zia Ur Rehman, Angelika Doetzlhofer

DOI 10.64898/2026.08.19.745776

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologyNature CommunicationsPeer-reviewedSep 1, 2025

The Notch ligand Jagged1 plays a dual role in cochlear hair cell regeneration.

Xiaojun Li, Charles Morgan, Lin Li…·Angelika Doetzlhofer

This study shows that Jagged1/Notch signaling maintains cochlear supporting cell progenitor-like characteristics and metabolic genes, and its inhibition enhances hair cell regeneration.

13 citationstop 1%

mousebulk RNA-seq

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NeurosciencebioRxivPreprintMay 29, 2025

Title: The RNA-binding protein TRIM71 is essential for hearing in humans and mice and regulates the timing of auditory sensory organ development

Xiaojun Li, Lin Li, Charles Morgan…·Angelika Doetzlhofer

This study identifies TRIM71 as essential for hearing in humans and mice, showing it regulates the timing of auditory sensory organ development and prevents premature hair cell differentiation.

DOI 10.1101/2025.05.29.656801

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 12, 2023

Reactivation of the progenitor gene Trim71 enhances the mitotic and hair cell-forming potential of cochlear supporting cells

Xiaojun Li, Charles Morgan, Prathamesh T. Nadar‐Ponniah…·Angelika Doetzlhofer

This study shows that reactivating Trim71 enhances the regenerative potential of cochlear supporting cells by promoting de-differentiation and hair cell formation.

DOI 10.1101/2023.01.12.523802

mouseexperimental assay

𝕏 PostBluesky