Author

Leilei (Polly) Chen

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Chi Ho Lin· 1 shared Daniel G Tenen· 1 shared Daryl Jin Tai Tay· 1 shared Henry Yang· 1 shared HuiQi Hong· 1 shared Jaymie Siqi Lin· 1 shared Julien Jean Pierre Maury· 1 shared Lihua Qi· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Chi Ho Lin

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1 paper

Recent·Most cited

An RNA editing/binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer

Lihua Qi, Yangyang Song, Tim Hon Man Chan, Henry Yang, Chi Ho Lin, Daryl Jin Tai Tay, HuiQi Hong, Jaymie Siqi Lin, Vanessa Hui En Ng, Julien Jean Pierre Maury, Daniel G Tenen, Leilei (Polly) Chen

This study reveals a non-editing gene regulatory role of ADARs in cancer by enhancing miR-27a processing, which represses METTL7A expression, highlighting a new therapeutic target.

Nucleic Acids Research · Jul 29, 2017Peer-reviewedCancer Biology