Hepatic stellate cell FXR signaling regulates context-dependent functions in liver homeostasis and fibrosis.
Manjula Vinod, Francesco Paolo Zummo, Céline Gheeraert, Zouriatou Gouda, Sandra Courquet, Emilie Dorchies, Lena Thuret, Marie Lapage, Loïc Guille, Marie Bobowski, Charlène Pourpe, Victor Launay, Mehdi Derhoudi, Amélie Bonnefond, Delphine Eberlé, , Alexandre Berthier
The paper investigates the role of FXR signaling in hepatic stellate cells (HSCs) during liver homeostasis and fibrosis, showing its impact on gene expression and anti-fibrotic effects.
bioRxiv · Aug 31, 2026 · PreprintMolecular Biology