Céline Gheeraert

The paper investigates the role of FXR signaling in hepatic stellate cells (HSCs) during liver homeostasis and fibrosis, showing its impact on gene expression and anti-fibrotic effects.

This study identifies a circadian clock-controlled signaling pathway that drives hepatic stellate cell activation in liver fibrosis, offering potential drug targets and a basis for chronotherapeutic strategies.

This study shows that HDAC inhibition by trichostatin A disrupts β-cell function and identity through epigenome-wide remodeling in both mouse and human β-cell models.

This paper maps nuclear receptor expression in mouse liver across time and space using single-cell RNAseq data.