Growth control through regulation of insulin-signaling by nutrition-activated steroid hormone
Kurt Buhler, Jason Clements, Mattias Winant, Lenz Bolckmans, Veerle Vulsteke, Patrick Callaerts
This study identifies a nutrient-dependent mechanism by which 20-hydroxyecdysone regulates insulin signaling in Drosophila through the fat body and IPCs, revealing dual roles of 20E in growth regulation.
Development · Jan 1, 2018Peer-reviewedDevelopmental Biology