Author

Jason Clements

KU LeuvenORCID 0000-0002-8901-784XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Kurt BuhleriD· 2 shared Mattias WinantiD· 2 shared Patrick CallaertsiD· 2 shared Veerle Vulsteke· 2 shared Korneel HensiD· 1 shared Lenz Bolckmans· 1 shared Sofie De GroefiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 19 mutual co-author links

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2 shared papersGenetics

Kurt BuhlerORCID

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2 papers

Recent·Most cited

Genome-wide analysis identifies Homothorax and Extradenticle as regulators of insulin in Drosophila Insulin-Producing cells

Mattias Winant, Kurt Buhler, Jason Clements, Sofie De Groef, Korneel Hens, Veerle Vulsteke, Patrick Callaerts

The paper uses GWAS on dilp expression data to identify genetic regulators in Drosophila IPCs, finding Homothorax and Extradenticle as key regulators of dilp expression.

PLoS Genetics · Sep 12, 2022Peer-reviewedGenetics

Growth control through regulation of insulin-signaling by nutrition-activated steroid hormone

Kurt Buhler, Jason Clements, Mattias Winant, Lenz Bolckmans, Veerle Vulsteke, Patrick Callaerts

This study identifies a nutrient-dependent mechanism by which 20-hydroxyecdysone regulates insulin signaling in Drosophila through the fat body and IPCs, revealing dual roles of 20E in growth regulation.

Development · Jan 1, 2018Peer-reviewedDevelopmental Biology