Irx1 and Irx2 play dose-dependent cooperative functions in mammalian development
Sepideh Sheybani-Deloui, Leo Xu, Lijuan Hu, Qiongjing Yuan, Joe Eun Son, Kyoung-Han Kim, Weifan Liu, Rong Mo, Xiaoyun Zhang, Lijun Chi, Paul Delgado-Olguı́n, Chi‐chung Hui
This study investigates the dose-dependent cooperative roles of Irx1 and Irx2 in mouse development, revealing distinct phenotypic outcomes from their genetic ablation.
bioRxiv · Oct 3, 2022 · PreprintDevelopmental Biology