Kyoung-Han Kim

Conservation and divergence of transcriptional heterogeneity in the cardiac conduction system

This study compares transcriptional heterogeneity in the cardiac conduction system across species and developmental stages using single-cell and spatial transcriptomic data.

Sex- and ketogenesis-dependent effects of intermittent fasting against diet-induced obesity and fatty liver disease

This study shows that intermittent fasting improves systemic metabolism regardless of ketogenesis but has sex-specific hepatic benefits requiring ketogenesis in mice.

Circadian reprogramming of adipose progenitor cells regulates intermittent fasting-mediated adipose tissue remodeling and metabolic improvement

This study shows that intermittent fasting reduces WAT fibrosis and improves metabolism in aged mice by modulating adipose progenitor cell circadian rhythms.

Irx1 and Irx2 play dose-dependent cooperative functions in mammalian development

This study investigates the dose-dependent cooperative roles of Irx1 and Irx2 in mouse development, revealing distinct phenotypic outcomes from their genetic ablation.

Deficiency of Irx5 protects mice from diet-induced obesity and associated metabolic abnormalities

This study shows that Irx5 deficiency in mice leads to reduced body mass and resistance to diet-induced obesity through increased metabolic rate and decreased adiposity.