Author

Leon Gabriel Straub

Department of Pharmacology, University of Virginia School of Medicine;Primary ORCID profile (0000-0001-6738-0130 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Leon Gabriel StraubiD1 paper · The University of Texas Southwestern Medical Center

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Hong ZhouiD· 1 shared Huiqiao Li· 1 shared Jieyi MengiD· 1 shared Shangang ZhaoiD· 1 shared Yanru Deng· 1 shared Yi ZhuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBioengineering

Hong ZhouORCID

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1 paper

Recent·Most cited

Transferrin receptor binding valency determines the circulating half-life and weight-loss efficacy of Fc-FGF21 in TfR-humanized mice

Hong Zhou, Yanru Deng, Huiqiao Li, Jieyi Meng, Leon Gabriel Straub, Shangang Zhao, Yi Zhu

This study shows that Fc-FGF21's weight-loss efficacy depends on its circulating half-life, which is influenced by hTfR binding valency and BBB transport.

bioRxiv · Nov 4, 2026 · PreprintBioengineering