Author

Leon Sheynkman

University of Virginia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:long-read sequencing· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Gloria SheynkmaniD· 2 shared Adam FrankishiD· 1 shared Alejandro PaniaguaiD· 1 shared Alessandra Martinez-Martin· 1 shared Ali MortazaviiD· 1 shared Alison D. TangiD· 1 shared Alla MikheenkoiD· 1 shared Alyssa Cousineau· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Gloria SheynkmanORCID

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2 papers

Recent·Most cited

Systematic assessment of long-read RNA-seq methods for transcript identification and quantification

Francisco J. Pardo-Palacios, Dingjie Wang, Fairlie Reese, Mark Diekhans, Sílvia Carbonell Sala, Brian A. Williams, Jane E. Loveland, Maite De María, Matthew S. Adams, Gabriela Balderrama-Gutierrez, Amit K. Behera, José M. González, Toby Hunt, Julien Lagarde, Cindy Liang, , Angela Norie Brooks

Benchmarking six long-read RNA-seq protocol-platform combinations and 14 tools across human, mouse, and manatee shows read length and accuracy drive isoform detection, depth drives quantification.

Nature Methods · Jun 7, 2024Peer-reviewedGenomics✦ In-depth digest

Characterization of protein isoform diversity in human umbilical vein endothelial cells (HUVECs) via long-read proteogenomics

Madison Mehlferber, Erin D. Jeffery, Jamie Saquing, Ben T. Jordan, Leon Sheynkman, Mayank Murali, Gaël Genet, Bipul R. Acharya, Karen K. Hirschi, Gloria Sheynkman

The paper uses long-read proteogenomics to characterize protein isoform diversity in HUVECs, identifying novel transcripts and isoforms with potential functional implications.

RNA Biology · Dec 1, 2022Peer-reviewedSystems Biology