Lipopolysaccharide lateral mobility in the Gram-negative bacterial outer membrane is confined and governed by interactions within the conserved Lipid A anchor
Joe Nabarro, Rosalyn M. Leaman, Samuel Lenton, Leonore Mantion, Richard J. Spears, Mark Christopher Coles, Dmitri O. Pushkin, Martin A. Fascione, Christoph G. Baumann
This study shows lipopolysaccharide in Gram-negative bacteria is laterally confined in the outer membrane due to magnesium and hydrophobic interactions, a feature conserved across species.
The EMBO Journal · Feb 17, 2026Peer-reviewedMicrobiology