Martin A. Fascione

This study shows that expressing rat CMAH in prostate cancer cells leads to Neu5Gc presentation on cell-surface glycans, which can be transferred to neighboring cells, suggesting a bystander effect in the tumor microenvironment.

This paper investigates why aryl sulfatases are inhibited by sulfamate warheads while carbohydrate sulfatases are not, using structural and computational analyses.

This paper reconstructs the complete nicotine biosynthesis pathway in vitro and in planta, identifying key enzymes and providing structural insights.

This study shows lipopolysaccharide in Gram-negative bacteria is laterally confined in the outer membrane due to magnesium and hydrophobic interactions, a feature conserved across species.

This study shows that the androgen receptor and MYC work together to control the production of Siglec-7 ligands in prostate cancer by regulating sialylation and glycopeptide profiles.

This study shows Escherichia coli maintains outer membrane homeostasis through growth-independent LPS turnover via vesicle release, challenging existing models of OM organization.

The paper introduces BOCTAG, a method to label glycoproteins in specific cell types within mixed cultures, enabling analysis of cell-specific glycosylation.