NeurosciencebioRxivPreprint
A systems approach uncovers drivers of the multifocal emergence of an astrocyte state contributing to cognitive decline in Alzheimer's disease
Natacha Comandante-Lou, Tsering D Lama, Sarah E. Heuer…·Philip L. De Jager
The paper identifies a novel astrocyte state linked to cognitive decline in Alzheimer's disease and validates its regulators through multi-modal analysis and mechanistic experiments.