Hongyan Zou

This study identifies how GBM cells use Plexin-D1 and Plexin-B2 to gain mechanocompliance, enabling immune-silent invasion through tissue.

This study identifies cortical tension as a mechanical barrier that prevents premature neuronal differentiation during neurogenesis, showing that reducing it accelerates neuronal lineage commitment and differentiation.

This paper develops a 3D brain vascular niche model to study GBM invasion and gene signatures, revealing glia-vascular contact influences transcriptional adaptation and poor prognosis.

The paper identifies a novel astrocyte state linked to cognitive decline in Alzheimer's disease and validates its regulators through multi-modal analysis and mechanistic experiments.

This study shows GBM cells use Plexin-B2 to regulate membrane tension and mechano-electrical coupling for migration through confined spaces.

This study identifies AhR as a regulator of axon regeneration by balancing stress and growth responses after injury, showing that its inhibition promotes regeneration in nerve and spinal cord injury models.

This study identifies Plexin-B2 as a regulator of cell mechanics during multicellular organization, showing its role in modulating cell stiffness, contractility, and differentiation in human stem and progenitor cells.