TENM4 is an essential transduction component for touch
Mohammed A. Khallaf, Angela Tzu-Lun Huang, Letizia Dalmasso, Sampurna Chakrabarti, Rowena Groeneveld, Yinth Andrea Bernal Sierra, Jonathan Alexis García-Contreras, Emilie Nello, Anja Schütz, Valérie Bégay, Alessandro Santuz, Sarah Hedtrich, Wei Hong Zhong, Christina Schiel, Steven J. Middleton, , Gary R. Lewin
This study identifies TENM4 as an essential extracellular linker protein for mechanotransduction in mechanoreceptors, showing its role in touch sensitivity.
bioRxiv · Oct 10, 2024 · PreprintNeuroscience