Alessandro Santuz

This study shows that reduced gravity reveals a proprioception-dependent mechanism for locomotor state expression in humans and mice.

The paper identifies Pitx2+ ascending propriospinal neurons in mice and shows their role in precise limb movements during skilled locomotion.

This study identifies TENM4 as an essential extracellular linker protein for mechanotransduction in mechanoreceptors, showing its role in touch sensitivity.

The paper examines how older adults adjust muscle synergies during gait perturbations, finding that four core synergies are preserved but modified in timing and muscle contribution.

This study shows that ascending proprioceptive information from the spinal cord to the brain is essential for responding to external perturbations during locomotion.

This study examines sex-specific differences in muscle activation patterns during locomotion in young and older adults using muscle synergies.

This study shows that mice can brake and turn during optogenetic stimulation of the MLR, with speed and turn angle scaling to pre-turn speed.

This study compares muscle activation patterns during treadmill and overground locomotion, finding that treadmill movement results in more regular and temporally shifted motor primitives.

The paper investigates how muscle synergies change with locomotion speed, finding that high-speed movement uses simpler, wider motor primitives for robust control.

This paper investigates pitfalls in fractal analysis of EMG data during mouse locomotion and provides recommendations to avoid misinterpretation of Higuchis fractal dimension and Hurst exponent.

This study shows that increased enthalpy efficiency of the soleus muscle during running explains improved running economy after training.

This study shows that older adults and those facing perturbations produce more stable muscle control signals during locomotion, enhancing robustness in challenging conditions.

The paper examines how muscle spindle feedback affects the modular organization of locomotion in mice, showing that proprioceptive input is crucial for maintaining motor function during walking and swimming.