Exploring the activation mechanism of the Mic60 subcomplex governing mitochondrial crista junctions
Evangelia Nathanail, Max Ruwolt, Gillian Dornan, Wiebke Y. Mikalo, Debora Elzha Aprillia Liu, Christina Schiel, Altan Tekgül, Abigail Hays Lewis, Karina von der Malsburg, Tobias Bock-Bierbaum, Volker Haucke, Séverine Kunz, Martin van der Laan, Fan Liu, Oliver Daumke
This study identifies structural elements and dynamics of the Mic60-Mic19 subcomplex crucial for MICOS assembly and crista junction formation.
bioRxiv · Oct 5, 2026 · PreprintMolecular Biology