A Human Angelman Syndrome Class II Pluripotent Stem Cell line with Fluorescent Paternal UBE3A Reporter
Gautami R Kelkar, Samantha R. Stuppy, Dilara Sen, Z. Begum Yagci, Linna Han, Lexi Land, Jessica K. Hartman, Albert J. Keung
This paper develops a human pluripotent stem cell line with a fluorescent UBE3A reporter to monitor paternal UBE3A expression during neuronal maturation and test reactivation strategies.
Frontiers in Cell and Developmental Biology · Aug 29, 2025Peer-reviewedCell Biology