Author

Samantha R. Stuppy

North Carolina State UniversityORCID 0000-0002-2652-0384Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Adam Blair YankeiD· 1 shared Albert J. KeungiD· 1 shared Brian O. DiekmaniD· 1 shared Dilara SeniD· 1 shared Douglas H. PhanstieliD· 1 shared Gautami R Kelkar· 1 shared Jacqueline ShineiD· 1 shared Jeremy D. BurgessiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Adam Blair YankeORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintSep 29, 2026

Mapping the response of primary human chondrocytes to an osteoarthritis-relevant stimulus by single-cell RNA sequencing

Samantha R. Stuppy, Jacqueline Shine, Susan D’Costa…·Brian O. Diekman

This study uses single-cell RNA sequencing to analyze how fibronectin fragment treatment alters chondrocyte states and transcriptional programs in primary human cells.

DOI 10.64898/2026.09.24.754148

humanscRNA-seq

Cell BiologyFrontiers in Cell and Developmental BiologyPeer-reviewedAug 29, 2025

A Human Angelman Syndrome Class II Pluripotent Stem Cell line with Fluorescent Paternal UBE3A Reporter

Gautami R Kelkar, Samantha R. Stuppy, Dilara Sen…·Albert J. Keung

This paper develops a human pluripotent stem cell line with a fluorescent UBE3A reporter to monitor paternal UBE3A expression during neuronal maturation and test reactivation strategies.

3 citations

humanscRNA-seq